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ANTIULCER CLEOME PDF

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In vivo antiulcer and in vitro antioxidant activity of Barleria gibsoni was .. and characterization of polyphenol oxidase from leaves of Cleome gynandra L. Food . Protective effect of standardized extract of Cleome viscosa against Animals; Anti-Ulcer Agents/administration & dosage; Anti-Ulcer. Research Journal of Pharmacognosy and Phytochemistry. Delivering full text access to the world’s highest quality literature.

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Sections of tissue from stomachs were examined histopathologically to study the antiulcerogenic activity of B. Antlulcer the many side effects of modern medicine, the initial acquisition of fewer side effects, and medication of indigenous drugs, it should be considered as a better alternative for the treatment of peptic ulcer. The ethanol EBG leaves demonstrated decreasing oxidative stress and increasing percentage preventive index compared to ascorbic acid and omeprazole, respectively.

Purification and characterization of polyphenol oxidase from leaves of Cleome gynandra L. A significant decrease was observed in the DPPH radical activity due to the scavenging ability of the extracts. Extract obtained by Soxhlation showed higher total phenolic and flavonoid contents.

In pyloric ligation-induced ulcer model, oral administration of leaves in two different doses antiucer significant reduction in ulcer index, gastric volume, free acidity, and total acidity as compared to the control group, whereas omeprazole as reference standard drug showed a significant reduction in ulcer index, gastric volume, free acidity, and total acidity [ Table 2 ].

Thus, the objective of the present investigation was to evaluate in vivo antiulcer and in vitro antioxidant activity of Barleria gibsoni leaves extract EBG. By conversion of the unpaired electrons to paired electron by hydrazine due to the hydrogen donating ability of the extract. Flavonoid content and antioxidant activities from Cinnamomum species.

One milliliter of Folin—Ciocalteu phenol reagent was added to the mixture and shaken. J Pharmacol Exp Ther.

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Phytochemical Screening and Anti-Ulcer Activity of Cleomo Gynandra Linn

Two milliliters of 10 mM sodium nitroprusside in 0. Phytochemical screening was carried out to identify the secondary metabolites present in defatted ethanol EBG. All experiments were carried out during the light period A score for the ulcer was studied similar to pyloric ligation-induced ulcer model.

National Center for Biotechnology InformationU. Pyloric ligation-induced gastric ulcer In pyloric ligation-induced ulcer model, oral administration of leaves in two different doses showed significant reduction in ulcer index, gastric volume, free acidity, and total acidity antiulced compared to the control group, whereas omeprazole as reference standard drug showed a significant reduction in ulcer index, gastric volume, free acidity, and total acidity [ Table 2 ].

In vitro antioxidant activity and total polyphenolic content of Cyperus rotundus rhizomes. Allready Registrered Click to Login. The volume was then made up to the mark.

Chapman and Hall; Involvement of neutrophils and free radicals in the potentiating effects of passive cigarette smoking on inflammatory bowel disease in rats.

Using this gallic acid antiuler curve, the total phenolic content in B. The seeds and its oil have antihelminthic properties but they are ineffective in treating roundworm infections. These findings suggest that the leaves of B. A lower IC 50 value indicates a higher free radical scavenging activity. Support Center Support Center. Table 1 Phytochemical screening of B.

The ulceration in gastric mucosa was measured and scored.

Antiulcer Herbs

The isolation of bioactive compounds from B. Tambolihas pursuing Ph. The half maximal inhibitory concentration, m: The total phenolic content of the EBG was determined using gallic acid equivalence as described previously.

Ethanol extract of leaves attenuated the gastric volume, free acidity, cleomee acidity and ulcer index thus showing the anti-secretory mechanism.

Gallic acid equivalence, AlCl 3: The animals were housed in colony cages and maintained under standard environmental conditions: He has published and presented papers antiulcerr reputed National and International journals and conferences. Ethanol extract prepared from the leaves of B.

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This is the first ever report of antiulcer and antioxidant activities in B. Ethanol, methanol, gallic acid, Folin—Ciocalteu reagent, potassium ferricyanide, trichloroacetic acid, ferric chloride, ferrous chloride, sodium nitroprusside, sulfanilamide, o-phosphoric acid, naphthylethylenediamine dihydrochloride, sodium carbonate, sodium dihydrogen phosphate dihydrate, disodium hydrogen phosphate dodecahydrate, aluminum chloride, quercetin, L-ascorbic acid, and 2,2-diphenylpicrylhydrazyl DPPHwere obtained from HiMedia Laboratory and Research Lab, India.

AcanthaceaeBarleria gibsonigallic acid, L-ascorbic acid, pylorus ligation-induced ulcer model, quercetin. NO radical scavenging of EBG was carried out as previously described. The current treatment of peptic ulcer is mainly done with H 2 receptor antagonists, proton pump inhibitors, and antimuscarinics. The effect of antiukcer extract of Cleome viscosa linn.

Many medicinal plants contain higher phenolic compounds such as flavonoids, monophenols, and polyphenols.

Extract preparation The collected fresh matured leaves of B. Evaluation of anti-ulcer activity of methanolic extract of Terminalia chebula fruits in experimental rats. The whole herb is used in treatment of inflammation of the middle ear and applied on wounds and ulcers, so the research was to prove experimentally anti ulcer activity in whole plant of Cleome viscosa linn.

Abstract Cleome cleme linn.

RJPT – Antiulcer and Analgesic Activity of the Ethanol Extract of Cleome gynandra Linn Leaves.

The photometric evaluation of the antioxidant capacity of the ethanolic EBG leaves showed good antioxidant capacity [ Figure 3 ]. The collected fresh matured leaves of B.

From the present study, ethanol EBG results reveal that antioxidant and antiulcer activity is equipoint to that of omeprazole. However, more work is required for the isolation and characterization of the active principles responsible for these activities. In vitro antioxidant activity of the extracts was tested using 2,2-diphenylpicrylhydrazyl DPPHnitric oxide NO radical scavenging activity.